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Therefore, IGF-1 may indirectly modulate carbohydrate metabolism through GH suppression and enhancement of insulin action

Since vitamin B12 is derived from animal-based sources, individuals who do not eat meat or animal byproducts can experience deficiencies if they do not use supplemental sources

Here are the most common signs of B12 deficiency: Physical symptoms You feel tired and lack energy

The symptoms of a B-12 deficiency include numbness or tingling of the extremities, fatigue, weakness, anemia, swollen tongue, jaundice, difficulty walking, cognitive difficulties, memory loss and paranoia