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Long-term in vivo tracing demonstrated state transitions, exhibiting reversible microglial plasticity

This hypothesis has led to the establishment of stagings of sporadic Parkinsons disease based on the presence of -synuclein aggregates throughout the nervous system ( Regardless of the primary cause of the disease, there is broad consensus that the cellular mechanisms involved in cell death, along with inflammation and oxidative stress, play key roles in its development (Tansey et al., 2022

Researchers have raised the question of whether lotions and moisturizers containing gluten could trigger a reaction in the skin of people with celiac disease

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Biochem Biophys Res Commun 478, 162167

Furthermore, research indicates that exosomes can cross the blood-brain barrier, raising the possibility that exosomes from HACE patients may play a role in the pathogenesis of HACE by disrupting oxidative stress responses and activating neuroinflammatory pathways [14, 15]