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Many people find this entry-level dose produces noticeable benefits without need for adjustment

Balupillai A, Nagarajan RP, Ramasamy K, Govindasamy K, Muthusamy G

PMID: 42134514 Microbiologyopen2026 Apr;15(2):e70276

Additionally, in a monkey model of PD, GDNF infusion in the lateral ventricles or the striatum significantly improved motor function, which was associated with upregulation and regeneration of nigral dopaminergic neurons and their innervation to the striatum [45]

Ghazizadeh, Z., Hur, E

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