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Oligopeptide-51 and -55 : anti-hyperpigmentation peptides, studied for solar spots and senile lentigines Nonapeptide-1 : -MSH antagonist, melanogenesis inhibitor in cosmetic research Agouti signaling protein (ASIP) : physiological MC1R antagonist, oriented toward pheomelanin rather than eumelanin Experimental pigmentation models Studies classically use: murine B16 melanocytes (F10 line, F1 line for differentiation), primary human melanocytes (NHEM), melanocyte-keratinocyte co-cultures , pigmented skin equivalents (MelanoDerm, Phenion FT)

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