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In summary, supplementation with L-GSH in HIV-infected individuals with CD4+ T cell counts below 350 cells/mm3 can help restore redox homeostasis and cytokine balance, therefore aiding the immune system to control opportunistic infections.

206 208 Although Caspase-3 is a pro-apoptotic caspase, existing evidence shows that after treatment with chemotherapy drugs, GSDME can be cleaved and activated by caspase-3, leading to pyroptosis

Normally, SCFAs produced by beneficial gut microbiota regulate enzymes critical for the synthesis of serotonin and dopamine

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