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Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin and IGF-1 levels and increased lifespan

4-Measurement of Intracellular Ca 2+ Concentration Intracellular calcium concentration ([Ca 2+ ] i ) was measured using the fluorescent indicator fura-2

Beyond these structural changes, senescent cells also exhibit cell cycle arrest, remaining mostly in the G1 phase [20]