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However, the interplay between melatonin and these novel cell death pathways in the context of ovarian aging remains largely unexplored

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This pathway can be inhibited by the cell-survival signaling pathways mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) and phosphoinositide 3-kinase (PI3K)/Akt (protein kinase B), which may protect the cells against the cytotoxic effects of VPA [210]

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Growing clinical experience with amylin analogues has clarified the hormones importance as part of the integrated network governing body weight and metabolic homeostasis

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