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If the B complex decreases the pain, continue taking it until your pain has been stable (or you have been pain-free) for 2 weeks, and then stop

10.1038/s41584-020-00506-w

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This enzyme is required for the synthesis of the amino acid, methionine, from homocysteine

30 days (reconstituted) Mechanism Classification Primary Mechanism: NNMT (Nicotinamide N-methyltransferase) Inhibitor Target Enzyme: Nicotinamide N-methyltransferase Cellular Effect: Increases intracellular NAD+ and SAM levels Metabolic Pathway: NAD+ salvage pathway modulation Selectivity: Highly selective for NNMT (no cross-reactivity with related enzymes) Pharmacological Properties Route of Administration: Subcutaneous injection Bioavailability: High (subcutaneous)

However, brain imaging showed no ischemic changes, vascular inflammation, or optic nerve damage