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Chen X, Guo W, Chang Y, Chen J, Kang P, Yi X, et al

In Japanese patients with hyperuricemia who were studied in detail, heritable ABCG2 dysfunction was observed in up to half of the study population investigated, and its population-attributable contribution to hyperuricemia was as high as 30%, much higher than the contribution of non-genetic factors such as overweight/obesity, heavy alcohol consumption and aging

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This communication should include detailed description of the side effect (what symptoms are experienced, when they started, how severe they are), timing relative to IGF1 LR3 use (when was the last dose, how long after use did symptoms begin), any actions already taken (interventions tried, their effectiveness), and current status (whether symptoms are improving, stable, or worsening)

Luteolin prevents THP-1 macrophage pyroptosis by suppressing ROS production via Nrf2 activation