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Because B12 is water-soluble, excess amounts are safely excreted by the body

Vitamin B12 is naturally found in various food sources, including meat, fish, poultry, eggs, and dairy

Considering that FXR signaling is activated by CA but not by UDCA, the anti-diabetic action of BAs in Insr P1195L/ +/HFD mice might be mediated also by a FXR-independent mechanism

The peptides mechanism relies on beta-3 adrenergic receptor modulation and potentially other adipocyte-specific pathways

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