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[ref][ref][ref][ref] Brain atrophy: High homocysteine is associated with brain atrophy and cognitive decline in aging

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Parkinsons disease Parkinsons disease (PD) is a long-term neurodegenerative disorder that affects the motor system, characterized primarily by the death of dopaminergic neurons in the substantia nigra and the presence of intracellular aggregates of misfolded -synucleine (Lewy bodies) in the surviving neurons 54,55

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