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doi: 10.1016/S0361-9230(03)00074-1

Among these, the NOD-, LRR-, and pyrin domain-containing 3 (NLRP3) inflammasome plays a significant role in APAP-induced liver injury

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This includes cartilage degradation and the development of degenerative joint disease, collectively contributing to the discomfort and impaired mobility experienced by the bulldog