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20 Acknowledgements This research was supported by the National Cancer Institute of the United States through The University of Illinois at Chicago Cancer Center, Cancer Education and Career Development Program (R25-CA57699) and the Roswell Park Transdisciplinary Tobacco Use Research Center (RO1 CA100362 and P5OCA111236) as well as by the Canadian Institutes of Health Research (57897 and 79551)

Immunosuppression caused by smoking inhibits the effective activation of T cells, which also inhibit B cells to proliferate and produce antibodies, thus making humoral immunity incapable ( In conclusion, CS is a risk factor for developing severe illness and increasing mortality during the SARS-CoV-2 infection

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These total to 36 cpg in Clark County and 62 cpg in Washoe County

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