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FMN also modulates epigenetic regulators like the histone methyltransferase KMT2B, indirectly influencing immune gene expression and neuroimmune balance, emphasizing the broader regulatory role of the RFK pathway

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Its primary mechanism of action involves increasing the expression of Brain-Derived Neurotrophic Factor (BDNF) in the cerebral cortex and hippocampus, promoting neuroplasticity, the formation of new synapses, and neuronal survival

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Research from 2020 demonstrates seleniums capacity to reduce accumulation and toxicity of heavy metals by enhancing antioxidant enzyme activity, making it a crucial nutrient in comprehensive detox protocols [3] (Feng et al., 2020)