Wang et al (Wang et al., 2024b)
Knockouts of the ThDP transporter SLC44A4 in mice display an upregulation of genes associated with colonic inflammation, and increased susceptibility to dextran sodium sulfate-induced colitis, accompanied by significant weight loss and shortening of the colon (204)
In pigs, which are considered tolerant concerning iodine excess, high iodine doses up to 10 mg/kg caused a significant downregulation of NIS in the thyroid gland and, simultaneously, it decreased mRNA expression of clue antioxidative enzymes, such as SOD and GPx, either in the liver or in the kidney or in muscles (target tissues of thyroid hormone action), however without affecting lipid peroxidation [196]
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Treat dryness, laxity, and painful or unsatisfying sex with Emfemme non-invasive and effective.
[DOI] [PubMed] [Google Scholar] 29.Trudel L, Tomasetto C, Rio MC, et al