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Ionizing radiation damage and its early development in chromosomes

Interestingly, PHGDH also affects tumor biology independently of its effects in serine metabolism, for example, directly interacting with the RNA-binding protein Poly(rC)-binding protein 2 (PCBP2), and inhibiting its proteasomal degradation

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[DOI] [PMC free article] [PubMed] [Google Scholar] 47.Edo Y., Otaki A., Asano K

Increased 5-lipoxygenase expression and induction of apoptosis by its inhibitors in esophageal cancer: A potential target for prevention